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Topcat trial how to#
Topcat trial trial#
Topcat trial series#

Many trials are set up so nobody knows who's been allocated to receive which treatment. In most trials, a computer will be used to randomly decide which group each patient will be allocated to. While the treatments are different in the 2 groups, researchers try to keep as many of the other conditions the same as possible.įor example, both groups should have people of a similar age, with a similar proportion of men and women, who are in similar overall health. control group – where you'll be given an existing standard treatment, or a placebo if no proven standard treatment exists.treatment group – where you'll be given the treatment being assessed, or.If you take part in a clinical trial, you'll usually be randomly assigned to either the: Only carried out on medicines that have passed all the previous stages and have been given marketing licences – a licence means the medicine is available on prescription.Ĭontrol groups, randomisation and blinding.The safety, side effects and effectiveness of the medicine continue to be studied while it's being used in practice.Trials often last a year or more and involve several thousand patients.

The medicine is tested in larger groups of people who are ill, and compared against an existing treatment or a placebo to see if it's better in practice and if it has important side effects.

Carried out on medicines that have passed phases 1 and 2.

This is to get a better idea of its effects in the short term.

The new medicine is tested on a larger group of people who are ill.

Researchers start with small doses and only increase the dose if the volunteers do not experience any side effects, or if they only experience minor side effects.

Researchers test for side effects and calculate what the right dose might be to use in treatment.

The drug is being trialled in human volunteers for the first time.

A small number of people, who may be healthy volunteers, are given the medicine.

This will either be a dummy treatment (a placebo) or a standard treatment already in use. The medicines will usually be tested against another treatment called a control.

Topcat trial series#

What happens in a clinical trial? Testing a new medicineĪll clinical trials of new medicines go through a series of phases to test whether they're safe and whether they work.

you may experience unknown side effects from the treatment.

there may be restrictions on what you can and cannot do – for example, you may be asked to not eat, or not drink alcohol, for a period of time.

it can be time consuming – you may be expected to attend a number of screening and follow-up sessions, and some trials require you to stay overnight.

It's important to find out about the inconvenience and risks involved before you sign up, and to carefully weigh up whether it's worth it. Some trials do not offer payment and just cover your travel expenses. Some clinical trials offer payment, which can vary from hundreds to thousands of pounds depending on what's involved and expected from you. To hear other people's experiences of taking part in a clinical trial, visit : clinical trials. If you take part in a clinical trial, you may be one of the first people to benefit from a new treatment.īut there's also a chance that the new treatment turns out to be no better, or worse, than the standard treatment. It may benefit you, or others like you, in the future.

Topcat trial how to#

Multiple Sclerosis Society: be in a studyĬlinical trials help doctors understand how to treat a particular illness.

Topcat trial trial#

Cancer Research UK: find a clinical trial.Charitiesįor some health conditions, you can find out about clinical trials from the websites of charities. The World Health Organization's International Clinical Trials Registry Platform (ICTRP) provides access to clinical trials in countries all around the world. You can also search the Be Part of Research site to find trials relevant to you, and you can contact researchers yourself. The Be Part of Research website has information about clinical trials and other research from several different UK registers. You can also search for information on a number of websites and register your interest in taking part in research. You can ask your doctor or a patient organisation if they know of any clinical trials that you may be eligible to join. A clinical trial compares the effects of 1 treatment with another. It may involve patients, healthy people, or both.